Ten years later and things haven't advanced at all as far as I can tell. I'm still building tooling for class-based ontologies because that is what people understand and know how to work with. The semantic web remains a distant vision; scientific knowledge remains as un-integrated as ever.
The block-programming designs started here also made their way into the BioBike VPL, Enflame, and Vaguely. The source is on Github but it depends on a version of Mac Common Lisp and the Mac OS that has been obsolete for decades.